iS Clinical Super Serum Advance +

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Photo of Dr Kupetsky & expert advice for skincare products.

Expert Advice: This serum promotes even, healthy skin, utilizing Arbutin and Mushroom Extracts to provide safe and effective brightening perfect for hyperpigmentation or melasma.


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iS Clinical Super Serum Advance +

iS Clinical Super Serum Advance +

1 fl oz / Serum / Treatments & Serums

Regular price $95.00
Regular price Sale price $95.00
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Shipping calculated at checkout.

Fall Sale: 25% Off with code SHEER25

Product Benefits

  • Diminishes dark spots and scars
  • Brightens and evens skin tone
  • Helps reduce fine lines and wrinkles
Photo of Dr Kupetsky & expert advice for skincare products./>
                <p><b>Expert Advice: </b>This serum promotes even, healthy skin, utilizing Arbutin and Mushroom Extracts to provide safe and effective brightening perfect for hyperpigmentation or melasma.</p>
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Product Description

Brighten and protect skin with iS Clinical Super Serum Advance+.

A scientifically advanced, clinically proven formula that combines 15% Vitamin C with peptides, plus powerful botanical antioxidants and safe skin brighteners. Diminish dark spots and scars while reducing the appearance of fine lines and wrinkles.

Key Ingredient: Vitamin C and Hyaluronic acid

How to Use

Apply 3-4 drops to the palm of hand. Using fingertips, dab and smooth evenly over face and neck.


Water/Aqua/Eau, Ascorbic Acid, Hyaluronic Acid, Pentylene Glycol, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Calcium Pantothenate, Zinc Sulfate, Urea, Glucose, Guanidine HCl, Tripeptide-1, Glycerin, Phenoxyethanol, Asiaticoside, Asiatic Acid, Madecassic Acid.

Shipping & Returns

We offer free shipping and free samples on most U.S. order.
Qualified items ship the same day!

  • Orders placed Monday through Friday before 1:00pm EST containing only specified, qualified items will ship the same day.

    All orders are processed Monday through Friday, excluding US federal holidays.

      Orders are typically delivered within 3-5 business days from the order’s ship date, unless there are delays from the carrier.

      Orders being shipped to Hawaii and Alaska may take up to 45 to 65 days to be delivered

      Need it faster? Select Expedited Shipping at checkout! Please note that you will be responsible for expedited shipping charges.

      Sorry, we currently do not offer free international shipping. 

      Need to cancel your order?

      We begin preparing your package for shipment as quickly as possible. Should you need to cancel your order, you must cancel before 1:00pm EST on the day you purchased.

      If you placed an order after 1:00pm EST, you must cancel before 10:00am the following day. Cancellations or delivery fee refunds cannot be processed after 1:00pm EST.

       For cancellations, please visit:

      Returns Policy

      If you're not happy, we're not happy. If you are not completely satisfied with your purchase from SkincareEssentials, you may return it within 30 days.

      Please visit:

      Please include your name and order number, and we will gladly send you a return label. 

      Damaged Items

      We do our very best to ensure that every item in your order arrives safely! If your package was damaged in shipment by the carrier, please keep the box and the merchandise and notify us immediately by phone at 800-909-6696 or by email at with your order number. We will provide you with a label for a return. Once the damaged item is received, we will inspect it and the damaged items and your item will be replaced and shipped out to you as soon as possible.

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      Customer Reviews

      Based on 39 reviews
      Amazing Product!

      I love this stuff! I have melasma on my forehead, and it has helped lighten that up significantly. The only thing I don't love is that it's quite sticky, so use very sparingly!

      Works Great

      i love how lightweight this serum is and it absorbs so nicely. I truly see a difference in it evening out my complexion and dark spots. Will re-purchase!

      lisa m.

      I love my product! It work amazing

      Victoria A.
      Amazing serum. It works

      This serum is lightweight, easily absorbed and very effective. At first I thought it couldn’t possible be effective since it is so light but after a few weeks I saw a difference in my fine lines, luminosity and firmness as well as reduced redness. Very effective!

      Julia S.
      IS Clinical Super Serum Advance +

      I really like this products. I have bad acne and this has helped clear my skin, as well as fade pre-existing red marks. My skin looks luminous and healthy after applying it.

      Michelle C.
      A must have for your skincare routine

      This stuff is liquid gold! Even my esthetician noticed an improvement in my skin. You will not regret buying this, but you need to use it faithfully to see results.

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